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Which drugs need to be used to prevent children from opening the bottle

Sep 09 , 2021

The child-proof bottle is also called CRC (Child-Resistant Cap) packaging, which originated in the United States in 1970. The 'Poison Prevention Packaging Act' (PPPA) stipulates that products harmful to children must be packaged in child-safe packaging. The specific drugs and dietary supplement products involved include the following categories:


Which drugs need to be used to prevent children from opening the bottle

child resistant cap



1. The following human products intended for oral administration: aspirin; prescription drugs and controlled drugs; products containing more than 1 gram of acetaminophen, products containing 1 gram or more of ibuprofen; containing more than 66 mg of diphenhydramine base Equivalent products; and products containing more than 0.045 mg loperamide;

2. The liquid product contains more than 5% of methyl salicylate;

3. For liquids containing 250 mg or more of elemental iron, the concentration is 0.025% or higher by weight/volume; for non-liquids, the concentration is 0.05% or higher by weight/weight;

4. Products containing more than 5 mg lidocaine or 0.5 mg of dibucaine; e) human products containing 250 mg or more of naproxen or 50 mg of ketoprofen;

5. Fluoride-containing products and ethanol-containing mouthwashes. (See the description above.);

6. Human products containing more than 14 mg of minoxidil;

7. Any dosage form that can be taken orally on over-the-counter medicines (OTC), and any medicine that contains active ingredients previously only available through prescription.

8. Products containing imidazoline equal to or greater than 0.08 mg.

The above is the US "Poison Prevention Packaging Act" for drugs and dietary supplement products that must be bottle-proof for children to open. In addition, it also includes containers containing liquid nicotine, chemicals and cosmetics.


Source: US Consumer Product Safety Commission


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