Tablets have many hidden dangers of moisture absorption

The validity period of medicines is closely related to the storage environment. Different medicines have different moisture-proof methods. If they are damp, they will easily change the form of medicines, leading to deterioration or failure. For effervescent tablets that easily disintegrate and melt in contact with water, moisture-proof measures are more stringent, so how to prevent effervescent tablets from getting damp?

92mm palstic tube for effervescent tablet

Effervescent tablets contain disintegrants, which will quickly disintegrate in contact with water and produce a large amount of carbon dioxide. In the production, effervescent tablets are also added with solubilizing ingredients, which make it easier to absorb moisture. To prevent the tablet from getting damp, corresponding measures can be taken to control the pre-treatment, preparation process and final packaging of effervescent tablet:

On the one hand, the pharmaceutical extract is processed before the molding process, and moisture-absorbing ingredients are removed as much as possible or moisture-proof auxiliary materials are added to reduce the viscosity of the extract to facilitate molding;

On the other hand, the use of the molding process and the moisture-proof packaging technology of the effervescent tube reduces the hygroscopicity of the drug during the production and storage process, and increases the stability of the formulation.

The moisture-proof principle of the effervescent tube is mainly reflected in the tightness of the packaging and the desiccant cap. There is a small medicine compartment on the top of the cap to store the desiccant, which helps to protect the active ingredients in the effervescent tablet and keep the bottle inside. The environment is dry. In addition, the effervescent tube has strict requirements for sealing, water molecule control, moisture-proof performance, water vapor transmission rate, and moisture content of the desiccant, which can prevent the effervescent tablet from being damp, deteriorating or failing.

Drug safety is related to the physical and mental health of patients. In terms of effervescent tube moisture-proof and other functional design, pharmaceutical packaging material manufacturers have a long way to go. It is expected that the applicability and moisture-proof performance of effervescent tablet packaging will be greatly improved in the future.