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Sterilization method of high-density polyethylene bottle - cobalt 60 irradiation

Mar 15 , 2023

High-density polyethylene bottles are commonly used packaging for medicines. There are many ways to prevent bacteria in medicines. In addition to strict control of raw materials and production processes, packaging sterilization operations are also essential. Cobalt 60 irradiation sterilization It is a common method of sterilization.


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45ml plastic medicine bottle with CRC

Several requirements for material properties of tablet medicine bottles

50ml desiccant bottle


The so-called irradiation sterilization refers to the use of gamma rays or high-energy, high-power electron beams emitted by the decay of cobalt-60 radioactive sources to irradiate objects, and achieve the effects of material modification, sterilization and disinfection through the radiation effect. The devices required for irradiation are cobalt-60 and electron accelerators. Electron accelerators can shorten the sterilization time, which is one of the reasons why high-density polyethylene bottles choose this sterilization method.

Cobalt 60 irradiation sterilization has no special requirements for packaging materials, and can handle packaged and full-box finished products. After sterilization, it is directly loaded and transported away without disassembly and assembly, avoiding the risk of secondary pollution. Another advantage is that there are no chemical residues in the radiation sterilization process, because it uses radiation, so the item only receives the energy of the radiation. This is a physical disinfection process. No chemical substances are added and there is no direct contact with radioactive substances, so there is neither chemical residue nor radioactive contamination.

Three common colors of tablet medicine bottles

effervescent packaging

Molnupiravir for moisture-proof packaging of drugs two requirements

medicine cap


It should be noted that after cobalt-60 irradiation sterilization, the surface of most medicine bottles will turn slightly yellow, which will not affect the function of the packaging. On the whole, this sterilization method has a strong ability to penetrate the product. Through gamma sterilization, various microorganisms and pathogenic bacteria inside the snakeberry product can be flexible, and the microorganisms cannot reproduce rapidly in a short period of time. , It has been widely used in food, raw materials, medical products and other industries.


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