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Requirements for COP vials for cell-based drugs

Feb 16 , 2023

In recent years, the field of cell therapy has entered a period of rapid development. It has shown increasing application value in the fields of cancer, blood diseases, cardiovascular diseases, diabetes, Alzheimer's disease, and familial hypercholesterolemia. hotspots. As a high value-added drug, what are its requirements for COP vial packaging?


Requirements for COP vials for cell-based drugs

RTU(ready to use) 2ml COP vial


Application of COP vial in high pH value drug

5ml COP vial


Application of COP vial in high pH value drug

100ml COP injection vial


Packaging is accompanied by the distribution, transportation and storage period of drugs, and plays a very important role in the stability and safety of drugs. Cellular drugs refer to a class of compounds that kill cells by interfering with the basic metabolic processes of cells. A notable feature of this type of drug is that it contains protein components, which are easily adsorbed on the packaging surface, resulting in waste of drugs and affecting the dosage of drugs. Therefore, the packaging of cell-based drugs must have low protein adsorption.


Cellular drugs generally need to be stored in a liquid nitrogen environment, and an ultra-low temperature environment can ensure the activity of the drug. Therefore, COP vials must have good low temperature resistance to meet the storage requirements of such drugs.


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Disposable Intranasal Atomization Device


To sum up, low protein adsorption and low temperature resistance are the two basic requirements for cell-based drugs on COP vials, and they are also the two key properties to ensure the stability of drugs during storage. In addition, this kind of packaging also has very good chemical stability, and is not easy to change color after irradiation sterilization. It is a commonly used packaging for high-pH drugs and anti-tumor drugs.


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