Effervescent tablet is a new type of preparation, which originated from abroad and has been widely used in China in recent years. Due to the complex and difficult production process and high production cost, this dosage form has very strict requirements on packaging. Then as an effervescent tube as a special packaging for effervescent tablets, in order to prevent the medicine from being damp, denatured, and invalidated, a desiccant is usually placed in the bottle.
144mm*29mm effervescent tube packaging
But we also need to pay attention to the fact that the desiccant in the effervescent tube is sealed by white cardboard. There are certain requirements for the thickness and moisture content of the cardboard. If the cardboard is too thick, it will enhance the barrier effect on the desiccant and affect its moisture resistance. If the moisture content is too high, the desiccant will apply more moisture absorption performance to the cardboard, reducing the overall moisture resistance of the packaging internal environment. The quality requirements for effervescent tubes are in accordance with the national standard YBB00172004-2015 "Oral Solid Medicinal Low-density Polyethylene Moisture-proof Composite Bottle Caps", in which the requirements for cardboard are as follows: the moisture content is less than 6%, the The lead shall not exceed 0.0005%, and the drug contact surface shall be inspected under the ultraviolet lamp with a wavelength of 365mm and 254mm, and there shall be no flake fluorescence. The thickness is recognized in the industry as 0.46-0.55mm pure high-quality wood pulp white cardboard.
To sum up, the whiteboard must strictly meet the standard requirements, so as to ensure the moisture-proof performance of the desiccant, and then ensure the overall moisture-proof function of the effervescent tablet tube, and protect the health of users.
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