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Medications that meet these characteristics can use COP vials

May 17 , 2021

Drug packaging is an important part of drugs. Choosing suitable packaging for drugs is a prerequisite to ensure drug stability and patient health. However, there are always some drugs with special properties, which require special packaging to ensure drug stability. COP bottles (cyclic olefin pharmaceutical polymer bottles) are such a special kind of packaging.


Medications that meet these characteristics can use COP vials

100cc COP injection vial


COP is an optical material developed and produced by Zeon Corporation in Japan. It is used for medical optical components and high-end pharmaceutical packaging materials. It has high transparency, low birefringence, low water absorption, high rigidity, high heat resistance, and water vapor. Good airtightness and other characteristics, in line with FDA standards. Generally speaking, there are mainly the following types of drugs used in COP bottles:

1. High value-added drugs, and are very afraid of damage (such as lymphocyte antigens, hormone drugs, anesthetics). COP has excellent mechanical properties, higher tensile strength and elastic modulus than PC, not easy to break, and easy to transport;

2. Drugs with PH value greater than 9. Drugs with high PH value will peel off when stored in glass bottles, and metal ions will be precipitated, which is not conducive to the storage of drugs. COP is a green plastic with very little impurity content, so there is no need to worry about the analysis of debris. And medical device requirements;

3. Drugs that are easily adsorbed on the glass surface (such as protein-based biopharmaceuticals, vaccines, etc.). Protein-based drugs will be adsorbed on the glass surface, which is not conducive to the precise control of drug dosage. COP has low protein adsorption characteristics, which can ensure the accuracy of drug dosage;

4. Other drugs that are easily oxidized.

In foreign countries, the application of COP bottles in pharmaceutical packaging has become very common, and it is also in the stage of gradual popularization in China. In order to ensure the stability of drug storage and better ensure the value of the drug, the above several drugs can be packaged in COP vials.


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