Molnupiravir was jointly developed by Merck and Ridgeback for the treatment of COVID-19 in patients infected with SARS-CoV-2, and has received emergency approvals in India, the United Kingdom, the United States and other places. This drug is a capsule preparation. As a special dosage form, how can its drug packaging be moisture-proof?
Capsule preparation is a capsule made of special film-forming materials (such as gelatin, cellulose, polysaccharide, etc.), into which the contents (such as powder, liquid drugs, etc.) or doses are loaded. This drug is very sensitive to water molecules, and it is easy to stick and deliquescence after being wet, which affects the efficacy of the drug. The pharmaceutical packaging used for this drug must have very good moisture resistance.
Medicinal plastic bottle is a commonly used packaging method for capsule preparations. In order to prevent the drug from getting wet, a desiccant will be placed in the moisture-proof packaging of the drug, which can absorb the water molecules inside the package and maintain the stability of the internal environment. The desiccant is mainly based on silica gel and molecular sieve, or a mixture of the two in equal proportions. The silica gel desiccant can effectively control the number of water molecules for a long time. effect.
The desiccant in the moisture-proof packaging of medicines is mostly packaged in bags. With the continuous evolution of packaging, packaging with more novel functions has gradually appeared. A small medicine warehouse is designed on the bottle cap to store the desiccant, which can prevent Direct contact between the drug and the desiccant can also prevent children from accidentally eating the desiccant. This novel design of packaging also increases the added value of drugs and becomes the choice of more and more pharmaceutical companies.
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