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cycloolefin polymer bottle

Jan 10 , 2019

The tradition is mainly based on glass products, and it is selected according to the characteristics of the drug to meet the rubber stopper. The precipitation of alkali metal ions in the glass leads to an increase in the pH of the drug solution, and may also precipitate harmful substances such as arsenic and antimony. According to industry insiders, the use of low-quality glass bottles to pack sodium bicarbonate, ribavirin and other alkaline injections are prone to stripping, packaging vitamin B6 is prone to white spots. The sodium-calcium glass bottle was filled with sodium bicarbonate injection for 6 months and the debris was visible to the naked eye. In summary. Glass lyophilized packaging cannot be used to hold alkaline drugs.


cycloolefin polymer

COP vials


At present, all kinds of medicinal packaging glass used in China are sorted according to various performances, from high to low: neutral borosilicate glass, high borosilicate glass, low borosilicate glass, soda lime glass. Neutral borosilicate glass is the preferred material for injection packaging, and it has long been popular in developed countries. Neutral borosilicate glass has been monopolized by the technology of three foreign companies. The price of entering the domestic market is more than ten times that of ordinary medicinal glass. The price of domestically qualified neutral borosilicate glass is also much higher than that of low borosilicate glass and soda lime glass.


cycloolefin polymer

COP vial neck


New lyophile packaging COP materials are less expensive than neutral borosilicate glass. Cyclo olefin polymer is a cyclic olefin polymer with strong chemical stability, high strength, low adsorption, stable pH and alkaline drug, transparency of up to 95% and glass material of 82%. It can also be stored at a temperature of 230 °C while it is cryopreserved, and it can effectively reduce the noise generated by the bottle during the production process.

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