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Can lyophilization vials use plastic bottle?

May 03 , 2018

The test results and COP properties indicate that the vials seem to be especially appropriate for Larger molecules.

 i.e. protein-derived compositions (adsorption, oxidation)


Can lyophilization vials use plastic bottle?

lyophilization vials-COP

Unbuffered solutions, low volume fill
Aggressive complexing agents i.e. Citric acid, EDTA
Solution being sensitive towards metal ions like Na, Al, B, Fe, Ti
Contrast media which contain radio isotopes tending to ion exchange
Lyophilization needed due to glass container limitations, i.e. high pH value
High potency and toxic drug solutions i.e. cytoxics, hGH (safety)



Can lyophilization vials use plastic bottle?

COP and glass bottle compare

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